Age-standardized characteristics out-of 86,149 women in the fresh NHS I within the 1994 and you can 94,715 feamales in the latest NHS II in 1995 by quintiles out-of magnesium, potassium, and you can calcium supplements intakes step 1
Design dos is actually modified for model 1 and intakes of potassium and you will calcium supplements (quintiles from grams/d)
Regarding the multivariate analyses, complete and you may dieting magnesium consumption have been inversely on the threat of total however, ischemic or hemorrhagic heart attack ( Table dos). The newest pooled multivariate RR having overall heart attack try 0.87 (95% CI: 0.78, 0.97; P-trend = 0.07) into testing of women from the highest that have low quintiles off total magnesium consumption; while new pooled multivariate RR toward testing from highest which have reduced quintiles regarding diet magnesium intake is 0.81 (95% CI: 0.69, 0.94; P-development = 0.001) getting full heart attack. Overall potassium consumption is actually inversely associated with danger of total but maybe not ischemic or hemorrhagic coronary arrest ( Desk step 3). To own comparison of women in the higher which have reasonable quintiles off overall potassium intake, the pooled multivariate RR for overall coronary attack try 0.89 (95% CI: 0.80, 0.99; P-development = 0.01). Multivariate RRs both for magnesium and you may potassium was basically attenuated when most of the step three nutritional elements were as part of the habits in addition (multivariate model 2). There clearly was no significant organization anywhere between total or dieting calcium consumption and you will total, ischemic, or hemorrhagic coronary attack ( Dining table 4). Multivariate RRs to have total magnesium (Extra Dining table step 1), complete potassium (Extra Table dos), full calcium supplements (Extra Table 3), fat reduction magnesium (Extra Desk 4), fat reduction potassium (Extra Desk 5), and weight reduction calcium (Supplemental Desk six) and you may risk of overall, ischemic, and you may hemorrhagic shots each cohort independently are given regarding extra situation.
Pooled RRs (95% CIs) of complete, ischemic, and hemorrhagic strokes because of the quintiles off total and you can dietary magnesium intake inside the 86,149 ladies in this new NHS I and you can 94,715 women in the fresh new NHS II step 1
Values are the n of cases. https://datingranking.net/spiritual-dating-sites/ Cox proportional hazards models were used to estimate RRs and 95% CIs. Model 1 was adjusted for age, calendar year, total calories (quintiles of kcal), BMI (in kg/m 2 ; <25, 25 to <30, or ?30), parental history of heart disease (aged ?60 y), alcohol intake (0, 0 to <5, 5 to <10, 10 to <15, or ?15 g/d), physical activity (<3, 3 to <9, 9 to<18, 18 to <27, or ?27 metabolic equivalent tasks/wk), smoking, postmenopausal hormone therapy, oral contraceptive use (never, past, or current), menopausal status (premenopausal or postmenopausal), aspirin (0 to <2 or ?2 pills/wk), multivitamin, history of hypertension, hypercholesterolemia, diabetes at baseline, and thiazide use (yes or no). NHS, Nurses' Health Study.
Pooled RRs (95% CIs) out of total, ischemic, and you will hemorrhagic shots because of the quintiles out-of complete and you may diet magnesium consumption in the 86,149 women in the NHS I and you can 94,715 feamales in the fresh NHS II step one
Values are the n of cases. Cox proportional hazards models were used to estimate RRs and 95% CIs. Model 1 was adjusted for age, calendar year, total calories (quintiles of kcal), BMI (in kg/m 2 ; <25, 25 to <30, or ?30), parental history of heart disease (aged ?60 y), alcohol intake (0, 0 to <5, 5 to <10, 10 to <15, or ?15 g/d), physical activity (<3, 3 to <9, 9 to<18, 18 to <27, or ?27 metabolic equivalent tasks/wk), smoking, postmenopausal hormone therapy, oral contraceptive use (never, past, or current), menopausal status (premenopausal or postmenopausal), aspirin (0 to <2 or ?2 pills/wk), multivitamin, history of hypertension, hypercholesterolemia, diabetes at baseline, and thiazide use (yes or no). NHS, Nurses' Health Study.